January Science Pub: Everything You Wanted to Know About CRISPR But Were Afraid to Ask
Every month we collect our Science Pub evaluations and every month we see CRISPR as a topic suggestion; you've waited long enough!
Come to January's Science Pub to learn about this fascinating and cutting edge gene editing technology.
You may have heard several stories in the news recently related to the relatively recent breakthroughs in gene editing thanks to CRISPR, or Clustered Regularly Interspaced Palindromic Repeats. This technology has the potential to treat genetically-defined diseases and we have three experts to discuss what this might look like for cancer and autism.
Come to the January pub to learn just what Clustered Regularly Interspaced Palindromic Repeats (CRISPR) is all about.
Dr. Michael Cole is a Professor in the Department of Molecular and Systems Biology in the Geisel School of Medicine at Dartmouth. He has spent over 35 yrs studying the mutations that drive cancer. He was the first to introduce CRISPR technology into the Dartmouth scientific community.
Bryan Luikart, PhD is an Associate Professor in the Department of Molecular and Systems Biology at The Geisel School of Medicine at Dartmouth. Dr. Luikart received a BS in Molecular and Cell Biology from Texas A&M Universty (1999), a PhD in Neuroscience from University of Texas Southwestern Medical Center under Luis Parada (2004), and completed postdoctoral training under Gary Westbrook at the Vollum Institute (2010). Dr. Luikart joined the Geisel School of Medicine at Dartmouth in 2011. Since joining the faculty at Geisel, Dr. Luikart studies how dysfunction of the autism predisposition gene, PTEN, impacts neuronal function. Further, the Luikart laboratory has developed CRISPR technology to target numerous genes that have been associated with autism in patients. In collaboration with Steve Fiering at Geisel they have generate novel gene knockout mice to model autism.
Elizabeth Sergison is the director of the newly established CRISPR Core at Dartmouth, a subset of the genetics and molecular biology shared resource. She received her B.A. in biological sciences from Mount Holyoke College and Ph.D. in molecular and systems biology from Dartmouth College. Her research involves using genome-wide CRISPR knockout screens to identify new tumor suppressor genes in breast cancer.